Rep Power: 0

Have 2003 Civic 150,000 miles, been taken care of. Been getting a multiple cylinder missfire, plugs and coils have been replaced, while driving when floored misses much worse almost felt like a possible restriction in the exhaust, maybe a plugged cat. Just didn't know if someone else has run into something similiar. Plug wires look OK, don't see any carbon tracking where they were grounding out. Any ideas?

 
Rep Power: 127

Sounds like you’ll have more codes than just multiple misfires. Have you done a compression test?