oh! you are trying to match gain for different sized drivers!
I thought you were trying ot just match gain for two subwoofers.
well, the bottom line is that no two drivers will have the same gain in your car! not if you want it to sound good
your tweeters will have a different efficiency than your mids will have a different efficiency than your subwoofers. youll inherrently have different gain. if you match them and your tweeters are more efficient, your music will sound like you put in a pair of infinity references
as for left and right, thats all a matter of phasing. which speakers are on axis, which are off axis, and your proximity to them.
you cna use your o-scope to match the levels if you relaly wanted to, though. youd play a sine wave through each output and check the wave amplitude. itll be the same when the levels are matched.
as for inter-eqiupment matching, thats for your ear to determine. I always try to maximize gain at the opening of the signal chain and have it small as possible at the end. this doesnt always work though. the idea is to have ZERO audible noise and not get distortion at high volumes.
the iasca or usac zero bit track helps here.
edit: reread the question, interpreted it differently. if you have an active crossover with a line driver, yes, the gai nworks basically the same way. radio volume, amp gain, and line driver, all they serve to do is boost output voltage. its not exactly the same, as your radio volume and line driver boost output voltage, and the amp gain was designed to match input voltage, but you still at the end see the results with a multimeter. empirical testing I still think is the best way to set them, with confirmation from the oscope.