All good points here. But let me add a couple things.
Don't go to Best Buy for either your install or your purchase. Yeah they're easy because you can say,"I want that, that, and that, and I want you guys to install it all on Thursday" plunk down your plastic and walk away with a smile. However, in my experience, much better prices can be found online - hell, most of the stereo stuff I use has been gotten off of Ebay. By all means go to Best Buy to look at the stuff, comparison shop, check prices, listen to the decks and speakers and talk to the techs, but I wouldn't look to them as a one stop shop. Anyway here's some specifics.
Amplifier wiring kit
Head on over to your local Wal-Mart and pick up their 0 gauge (may be call 1500-2000 watt) amp wiring kit. Last time I bought one it was like $35. You can't touch these for under $80 at Best Buy. This isn't overkill in case you ever want to add another amp, and plus the kit has everything you need.
Box building
Check this site out.
CarStereo.com
This is the help section where it has all kinds of formulas to determine the best sounding box size.
It has a little calculator (Sealed Speaker Enclosure Design Calculator) for figuring the optimal size of a box for any specific sub if you have a couple values from the sub manufacturer. Use the Calculator and enter in the Qts Vas, and Fs of your speaker - again get the tech specs from the speaker manufacturer webpage - and then enter the desired Qtc to get the interior volume of the box you want to build. Then take that value (called Vb) and use it in the Box dimensions calculator. Now this is easier than it sounds. Here's an example of my speaker specs.
My sub: Kenwood KFC-XW1202DVC (12 inch dual-voice coil sub)
Qts: 0.33
Vas: 3.23 (cubic feet)
Fs: 23 (Hertz)
Qtc: 0.9
(A value of 0.701 is true recorded sound, 0.9 gives a little more bass. Don't go higher than 1.1 or you will mechanically blow your speaker, think high compression pistons here.)
Hit Calculate.
The formula tells me that the optimal inner box volume for this sub is .516 cubic feet. Take that value and plug it into the Box Dimensions calculator along with two dimensions of your box (say height and depth in your case since you want a smaller footprint in your trunk) and it will calculate the remaining value. Add maybe an inch to one value - to account for how much space your sub takes up inside the box and you're done. For example
So I plug in these values:
14.5" x 14.5"
.516 (volume from the first calculation)
.75" (for my MDF)
and it tells me the last piece should be 6.77 inches. So I add an inch and the final exterior measurements of my box will be 14.5" x 14.5" x 8" to get the sound that I want - just a little heavier bass than it was recorded at.
Amplifier.
Get yourself a decent Mono amp (also called Class D), hook your two 10s up in a parallel wiring setup and enjoy the sound. Class Ds are expensive, so you can get similar results for less money with a decent 2-channel amplifier, again as long as you run the speakers in parallel. This means hooking them up together which decreases the load (Ohms). In otherwords, hooking two 8 ohm speakers up in parallel gives you a 4 ohm resistance, which the amp has an easier time powering.
If you got even one 10" subwoofer with two 4 ohm voice coils (called DVC, very common) you could hook them up in parallel, dropping your resistance to two ohms, and bridge your 2-channel amp to power them. That one 10" sub would pound harder than two SVC 10" subs on the same amp. Check the Speaker/Sub Wiring at the bottom of the site for how this is done. Again its a lot easier than it sounds.
I know its a lot of info, but PM me or post any other questions here if you have them. I'm happy to answer them. I've been doing car stereo installs as a hobby for a while now.